The Lyme Disease Project at U Penn

U-Penn Using PCR To Unlock Lyme Mysteries

Researchers at the University of Pennsylvania are looking to discover why some Lyme patients continue to exhibit objective signs of infection despite supposedly adequate antibiotic therapy.  To this end, they are seeking samples from patients for analysis.

Dr. H. Ralph Schumacher, Director of the Rheumatology-Immunology Center at the University of Pennsylvania  School of Medicine, is leading the Lyme project.  Dr. Schumacher is continuing the work previously performed by Drs. Manfred and Margaret Bayer at the Fox Chase Cancer Center in Philadelphia.  Funding is being provided by the Lyme Disease Association of New Jersey.

At the most basic level, the project will use the polymerase chain reaction (PCR) method to attempt detection of Borrelia burgdorferi (Bb), the causitive agent of Lyme disease, in urine and synovial fluid samples.  These results will be analyzed along with the patient's clinical, diagnostic and treatment data.

All samples sent to Dr. Schumacher must be submitted by a physician.

For more information, you may download the following scanned documents.

You will need Adobe Acrobat to view and print these documents.  Click here to download: 

For more information on this program, contact LD Association of NJ President Pat Smith at:

The Lyme Disease Network of NJ, Inc.
43 Winton Road
East Brunswick, NJ 08816